Inbreeding depression across the genome of Dutch Holstein Friesian dairy cattle
Creators
- 1. CGN, ABG, Wageningen University & Research, The Netherlands
Description
A paper produced in the frame of the H2020 project 677353 'Innovative Management of Animal GEnetic resources'
This study investigates the differences in inbreeding depression across the genome of Dutch Holstein Friesian cattle, by estimating dominance effects and effects of regions of homozygosity (ROH). Genotype (75 k) and phenotype data of 38,792 cows were used.
Genome-wide inbreeding depression was observed for all yield, fertility and udder health traits. After correcting for the effect of genome-wide homozygosity, dominance and ROH variance explained less than 1% of the phenotypic variance for all traits. Furthermore, dominance and ROH effects were distributed evenly along the genome. These findings suggest that, based on 75 k SNP data, there is little benefit of accounting for region-specific inbreeding depression in selection schemes.
Notes
Files
IMAGE-677353_2020a_Doekes_etal_GSE_inbreeding-depression-Holstein-cattle.pdf
Files
(7.8 MB)
Name | Size | Download all |
---|---|---|
md5:894aceff57d53065949c63cb4202373b
|
7.8 MB | Preview Download |