Published April 11, 2018
| Version v1
Journal article
Open
Trends in genome-wide and region-specific genetic diversity in the Dutch-Flemish Holstein–Friesian breeding program from 1986 to 2015
Creators
- 1. ABG, Wageningen University & Research, The Netherlands
- 2. ABG, CGN, Wageningen University & Research, The Netherlands
Description
A paper produced in the frame of the H2020 project 677353 'Innovative Management of Animal GEnetic resources'
Gene bank samples kept from 1986 to 2015 were used to study the trends in genome-wide inbreeding and kinship and corresponding effective population sizes. This revealed major changes due to the breeding program: the use of Optimal Contribution Selection indced a drop in inbreeding whereas the rate of inbreeding increased substantially after the onset of Genomic Selection (GS). Management of genetic diversity is recommended in GS schemes.
Notes
The Dutch Ministry of Economic Affairs also contributed financially to this study through the programs 'Kennisbasis Dier' (code KB-12-005.03.001) and 'WOT' (code WOT-03-003-056).
Files
IMAGE-677353_2018_Doekes_etal_GSE_region-specific-genetic-diversity.pdf
Files
(2.0 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:89eb2068434552b766c90e4a724aef53
|
2.0 MB | Preview Download |