Published July 5, 2021 | Version v1
Dataset Open

Interactive effects of ZnO nanoparticles and temperature on molecular and cellular stress responses of the blue mussel Mytilus edulis

Creators

  • 1. fangli.wu@uni-rostock.de
  • 2. inna.sokolova@uni-rostock.de

Description

We investigate the molecular and cellular stress responses of tissues (gills and digestive glands) in the mussels Mytilus edulis exposed for 21 days to either ambient (10 °C in winter and 15 °C in summer) or elevated (by 5 °C) temperature combined with different concentrations (0, 10, 100 µg l-1) of ZnO nanoparticles or dissolved zinc. In this data set, we used a biomarker-based approach focusing on oxidative stress indicators ( lipid peroxidation and protein carbonyls) and transcription pattern of marker genes in the pathways related to cell survival and proliferation (caspase 3, Bcl-2, p53, p38 and JNK) and inflammation (COX, NF-κB, and TGF-β) of M. edulis. 

Notes

Abbreviations: p53 – tumor protein p53; p38 – p38 mitogen-activated protein kinases; JNK – c-Jun N-terminal kinase; COX – Cyclooxygenase; Bcl-2 – B-cell lymphoma2; NF-κB – nuclear factor κB (p100/p105); TGF-β – transforming growth factor-beta.

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