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Published June 25, 2021 | Version v1
Dataset Open

Liquid Biopsy as a Diagnostic and Prognostic Tool for Women and Female Dogs with Breast Cancer

Creators

  • 1. Department of Molecular Biology, Cancer Molecular Research Laboratory (LIMC), FAMERP, São José do Rio Preto, Brazil
  • 2. Laboratory of Comparative and Translational Oncology (LOCT), Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Brazil
  • 3. Luiz de Queiroz College of Agriculture (ESALQ), University of São Paulo, Piracicaba, São Paulo, Brazil
  • 4. Department of Structural and Functional Biology, Institute of Biosciences of Botucatu, IBB/UNESP, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Contributors

Description

This dataset contains numerous analyses on genetic variants obtained from liquid biopsy of women and dogs with breast cancer (BC). Both core biopsy and plasma samples were processed for next generation sequencing (NGS) assay. The effectiveness of liquid biopsy in the diagnosis and follow-up of women and female dogs with BC was investigated. In this study, 55 and 35 BC samples were collected from women and female dogs, respectively. After obtaining core biopsy and plasma samples, DNA and ctDNA of tumor fragments and plasma were processed and submitted to the Genome Analysis ToolKit (GATK).

 

Files

Table S1 Panel of 168 genes involved in breast carcinogenesis in women and female dogs.pdf

Files (1.1 MB)