Dryad
Published March 8, 2019 | Version v1
Dataset Open

Data from: Analysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors

Creators

  • 1. University of Oxford
  • 2. Liverpool School of Tropical Medicine
  • 3. Centre de Recherche Entomologique de Cotonou (CREC)*
  • 4. Swiss Centre for Scientific Research
  • 5. Federal Ministry of Health
  • 6. Kenya Medical Research Institute
  • 7. Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale
  • 8. Abt Associates (United States)
  • 9. University of Nagasaki
  • 10. Public Health
  • 11. US President's Malaria Initiative, US Agency for International Development*

Description

The impact of insecticide resistance in malaria vectors is poorly understood and quantified. Here a series of geospatial datasets for insecticide resistance in malaria vectors are provided so that trends in resistance in time and space can be quantified and the impact of resistance found in wild populations on malaria transmission in Africa can be assessed. Data are also provided for common genetic markers of resistance to support analyses of whether these genetic data can improve the ability to monitor resistance in low resource settings. Specifically, data have been collated and geopositioned for the prevalence of insecticide resistance, as measured by standard bioassays, in representative samples of individual species or species complexes. Data are provided for the Anopheles gambiae species complex, the Anopheles funestus subgroup, and for nine individual vector species. In addition, allele frequencies for known resistance associated markers in the Voltage-gated sodium channel (Vgsc) are provided. In total, eight analysis-ready, standardised, geopositioned datasets encompassing over 20,000 African mosquito collections between 1957 and 2017 are provided.

Notes

1. standard WHO susceptibility test results for species complex and subgroup samples
1_standard-WHO-susc-test_complex-subgroup.csv
2. standard WHO susceptibility test results for single species
2_standard-WHO-susc-test_species.csv
3. standard CDC bottle bioassay results for species complex and subgroup samples
3_CDC-bottle-bioassay_complex-subgroup.csv
4. paired synergist bioassay results for species complex and subgroup samples
4_paired-synergist-bioassays_complex-subgroup.csv
5. intensity bioassay results for species complex and subgroup samples
5_intensity-bioassays_complex-subgroup.csv
6. Vgsc allele frequencies for species complex and subgroup samples
6_Vgsc-allele-freq_complex-subgroup.csv
7. Vgsc allele frequencies for single species
7_Vgsc-allele-freq_species.csv
8. paired Vgsc allele frequencies from dead and surviving mosquitoes after insecticide exposure
8_Vgsc-allele-freq_survivors-dead.csv

Files

1_standard-WHO-susc-test_complex-subgroup.csv

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Additional details

Related works

Is cited by
10.1101/582510 (DOI)