Published June 10, 2021 | Version v1
Journal article Open

Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs

  • 1. Plastic, Reconstructive and Hand Surgery Service, Lausanne University Hospital, University of Lausanne, Switzerland;
  • 2. Cell Production Center, Service of Pharmacy, Lausanne University Hospital, University of Lausanne, Switzerland
  • 3. Unit of Legal Affairs, Lausanne University Hospital, University of Lausanne, Switzerland
  • 4. Children and Adolescent Surgery Service, Lausanne University Hospital, University of Lausanne, Switzerland

Description

The complex management of severe burn victims requires an integrative collaboration of multidisciplinary
specialists in order to ensure quality and excellence in healthcare. This multidisciplinary care has quickly
led to the integration of cell therapies in clinical care of burn patients. Specific advances in cellular therapy
together with medical care have allowed for rapid treatment, shorter residence in hospitals and intensive
care units, shorter durations of mechanical ventilation, lower complications and surgery interventions,
and decreasing mortality rates. However, naturally fluctuating patient admission rates increase pressure
toward optimized resource utilization. Besides, European translational developments of cellular therapies
currently face potentially jeopardizing challenges on the policy front. The aim of the present work is to
provide key considerations in burn care with focus on architectural and organizational aspects of burn
centers, management of cellular therapy products, and guidelines in evolving restrictive regulations relative
to standardized cell therapies. Thus, based on our experience, we present herein integrated management of
risks and costs for preserving and optimizing clinical care and cellular therapies for patients in dire need.

Files

2021_JBCR.pdf

Files (2.6 MB)

Name Size Download all
md5:522ec4667b958917267c0f085ec7ddd1
2.6 MB Preview Download

Additional details

Funding

PHAS – Development of a new generation of bioengineered bandages 833594
European Commission