Dryad
Published January 8, 2018 | Version v1
Dataset Open

Data from: Effects of working-memory training on striatal dopamine release

Creators

  • 1. Karolinska Institute
  • 2. Departments of Integrative Medical Biology and Radiation Sciences, Umeå Center for Functional Brain Imaging (UFBI), 901 87 Umeå, Sweden.*
  • 3. Åbo Akademi University
  • 4. The WALTHAM Centre for Pet Nutrition
  • 5. Umeå University

Description

Updating of working memory has been associated with striato-frontal brain regions and phasic dopaminergic neurotransmission. We assessed raclopride binding to striatal dopamine (DA) D2 receptors during a letter-updating task and a control condition before and after 5 weeks of updating training. Results showed that updating affected DA activity before training and that training further increased striatal DA release during updating. These findings highlight the pivotal role of transient neural processes associated with D2 receptor activity in working memory.

Notes

MEMTRAIN1_CognitiveData
Cognitive test results
MEMTRAIN1_MRIDATA
T1 structural MRI data in Nifti format (defaced) for each participant
C0001PET1_DICOM
PET data of single scan
C0001PET2_DICOM
PET data of single scan
C0002PET1_DICOM
PET data of single scan
C0002PET2_DICOM
PET data of single scan
C0003PET1_DICOM
PET data of single scan
C0003PET2_DICOM
PET data of single scan
C0005PET1_DICOM
PET data of single scan
C0005PET2_DICOM
PET data of single scan
C0006PET1_DICOM
PET data of single scan
C0006PET2_DICOM
PET data of single scan
C0007PET1_DICOM
PET data of single scan
C0007PET2_DICOM
PET data of single scan
C0008PET1_DICOM
PET data of single scan
C0008PET2_DICOM
PET data of single scan
C0009PET1_DICOM
Image data from single PET scan
C0009PET2_DICOM
Image data from single PET scan
C0010PET1_DICOM
Image data from single PET scan
C0010PET2_DICOM
Image data from single PET scan
C0011PET1_DICOM
Image data from single PET scan
C0011PET2_DICOM
Image data from single PET scan
C0012PET1_DICOM
Image data from single PET scan
C0012PET2_DICOM
Image data from single PET scan
C0013PET1_DICOM
Image data from single PET scan
C0013PET2_DICOM
Image data from single PET scan
C0015PET1_DICOM
Image data from single PET scan
C0015PET2_DICOM
Image data from single PET scan
C0016PET1_DICOM
Image data from single PET scan
C0016PET2_DICOM
Image data from single PET scan
C0017PET1_DICOM
Image data from single PET scan
C0017PET2_DICOM
Image data from single PET scan
C0018PET1_DICOM
Image data from single PET scan
C0018PET2_DICOM
Image data from single PET scan
C0019PET1_DICOM
Image data from single PET scan
C0019PET2_DICOM
Image data from single PET scan
C0020PET1_DICOM
Image data from single PET scan
C0020PET2_DICOM
Image data from single PET scan
C0021PET1_DICOM
Image data from single PET scan
C0021PET2_DICOM
Image data from single PET scan
C0022PET1_DICOM
Image data from single PET scan
C0022PET2_DICOM
Image data from single PET scan

Files

C0001PET1_DICOM.zip

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Additional details

Related works

Is cited by
10.1126/science.1204978 (DOI)