Published June 7, 2021
| Version 1.0.0
Software
Open
Code and data for "Large-scale design and refinement of stable proteins using sequence-only models"
Authors/Creators
-
Singer, Jedediah M.1
- Novotney, Scott1
- Strickland, Devin2
- Haddox, Hugh K.3
- Leiby, Nicholas1
- Rocklin, Gabriel J.4
- Chow, Cameron M.3
- Roy, Anindya3
- Bera, Asim K.3
- Motta, Francis C.5
- Cao, Longxing3
- Strauch, Eva-Maria6
- Chidyausiku, Tamuka M.3
- Ford, Alex3
- Ho, Ethan7
- Mackenzie, Craig O.8
- Eramian, Hamed9
- DiMaio, Frank3
- Grigoryan, Gevorg10
- Vaughn, Matthew7
- Stewart, Lance J.3
- Baker, David3
- Klavins, Eric2
- 1. Two Six Technologies, Arlington, Virginia, USA
- 2. Department of Electrical and Computer Engineering, University of Washington, Seattle, Washington, USA
- 3. Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, Washington, USA
- 4. Department of Pharmacology and Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
- 5. Department of Mathematical Sciences, Florida Atlantic University, Boca Raton, Florida, USA
- 6. Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, Georgia, USA
- 7. Texas Advanced Computing Center, Austin, Texas, USA
- 8. Quantitative Biomedical Sciences Graduate Program, Dartmouth College, Hanover, New Hampshire, USA
- 9. Netrias, Arlington, Virginia, USA
- 10. Departments of Computer Science and Biological Sciences, Dartmouth College, Hanover, New Hampshire, USA
Description
Trained models, data, and code for "Large-scale design and refinement of stable proteins using sequence-only models", at https://www.biorxiv.org/content/10.1101/2021.03.12.435185v2