Comparison of optical coherence tomography angiography and narrow-band imaging using a bimodal endoscope
Creators
- 1. Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria, Medical University of Vienna, Christian Doppler Laboratory for Innovative Optical Imaging and Its Translation to Medicine, Vienna, Austria
- 2. University of Freiburg, Gisela and Erwin Sick Chair of Micro-optics, Department of Microsystems Engineering, Freiburg, Germany
- 3. Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria
Description
We present coregistered images of tissue vasculature that allow a direct comparison between the
performance of narrow-band imaging (NBI) and optical coherence tomography angiography (OCTA). Images
were generated with a bimodal endomicroscope having a size of 15 × 2.4 × 3.3 mm³ (l, w, h) that combines
two imaging channels. The white light imaging channel was used to perform NBI, the current gold standard for
endoscopic visualization of vessels. The second channel allowed the simultaneous acquisition of optical coher-
ence tomography (OCT) and OCTA images, enabling a three-dimensional (3-D) visualization of morphological
as well as functional tissue information. In order to obtain 3-D OCT images scanning of the light-transmitting fiber
was implemented by a small piezoelectric tube. A field of view of ∼1.1 mm was achieved for both modalities.
Under the assumption that OCTA can address current limitations of NBI, their performance was studied and
compared during in vivo experiments. The preliminary results show the potential of OCT regarding an improved
visualization and localization of vessel beds, which can be beneficial for diagnosis of pathological conditions.
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Wurster et al. - 2019 - Comparison of optical coherence tomography angiogr.pdf
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