Looking for the nexus between COVID, vaccines and thrombosis: anti-PEG antibodies

An explanatory mechanism for the thrombotic disorders detected after the administration of the COVID AZD1222 vaccine with recombinant adenovirus vectors is postulated:

"Platelet activation by adenoviruses, mediated by anti-PEG antibodies generated by the polysorbates themselves included in the vaccine, or generated in a previous administration of polysorbates or PEG to the vaccinated individual".

It is an immune interference whose biochemical basis is the chemical similarity between polysorbates and PEG with the repetitive structures on the surface of viruses, which causes cross-reactions between anti-PEG antibodies and viruses.

This same mechanism could govern the disseminated intravascular coagulation (DIC) observed in severe cases of COVID-19, due to the spike protein of coronaviruses.