Published April 15, 2019 | Version v1
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Synthesis of Perfluoroalkyl-Substituted Oxindoles through Organophotoredox-Catalyzed Perfluoroalkylation of N-arylacrylamides with Perfluoroalkyl Iodides

  • 1. School of Chemical Engineering, Guizhou Institute of Technology, Guiyang, 550003, P. R. of Chin

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Primary Data

An efficient process was developed for the perfluoroalkylation of N-arylacrylamides through an organocatalyzed photoredox/cyclization reaction of N-arylacrylamides with inexpensive perfluoroalkyl iodide reagents. The reaction employs an inexpensive organic dye, eosin Y, as the photoredox catalyst and is run under irradiation by a 26 W LED lightbulb.

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Journal article: 10.1055/s-0037-1611781 (DOI)