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Published October 17, 2019 | Version v1
Journal article Open

Critical assessment of recent trends related to screening and confirmatory analytical methods for selected food contaminants and allergens

  • 1. Department of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague 6 – Dejvice, Prague, Czech Republic
  • 2. Institute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5D, UK
  • 3. Wageningen Food Safety Research, PO Box 230, 6700 AE Wageningen, Akkermaalsbos 2 (building 123), 6708 WB Wageningen, the Netherlands Wageningen University, Laboratory of Organic Chemistry, Helix Building 124, Stippeneng 4, 6708 WE, Wageningen, the Netherlands
  • 4. CSEM SA, Center Landquart, Bahnhofstrasse 1, Switzerland
  • 5. Nanobiotechnology for diagnostics (Nb4D), Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish Council for Scientific Research (CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain
  • 6. Institute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5D, UK; School of Electronics, Electrical Engineering and Computer Science, Queen's University Belfast, Stranmillis Road, Belfast, UK
  • 7. Wageningen Food Safety Research, PO Box 230, 6700 AE Wageningen, Akkermaalsbos 2 (building 123), 6708 WB Wageningen, the Netherlands Wageningen University, Laboratory of Organic Chemistry, Helix Building 124, Stippeneng 4, 6708 WE, Wageningen, the Netherlands; Wageningen University, Laboratory of Organic Chemistry, Helix Building 124, Stippeneng 4, 6708 WE, Wageningen, the Netherlands

Description

Food contaminants monitoring is conducted in an intensive manner yet, there are still food safety scandals related to various chemical compounds. This fact highlights the need to review the requirements posed by the current legal framework on analytical methods performance and evaluate its application in published studies. Herein, we present an inventory including more than 470 publications on screening and confirmatory methods, which were used to control hazardous compounds such as pesticides, antibiotics, mycotoxins, aquatic toxins and allergens. Analytical performance characteristics, trends and state of the art, both merits and shortcomings, are critically discussed and summarized in excel tabulations. This repository highlights the ever-increasing use of screening methods and the necessity to confirm their performance by applying confirmatory methods. In conclusion, more effort is needed on validation and benchmarking, especially of newly developed technology such as smartphone-based methods, to avoid false-negative results and ensure that methods fit for purpose.

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Additional details

Funding

FoodSmartphone – Smartphone analyzers for on-site testing of food quality and safety 720325
European Commission