Published January 21, 2021
| Version v1
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Code for Bauer, R., Clowry, G. and Kaiser, M., 2021. Creative destruction: a basic computational model of cortical layer formation. Cerebral Cortex
Description
This code specifies a computational model that can account for the development of layer-specific neuron numbers in various different cortical structures. It is agent-based and is initiated from a small homogeneous pool of precursor cells. The file Lamination.java includes the main function that induces the activation of multiple "modules" within a gene regulatory network.
Notes
Instructions to run the code from Ubuntu 16.04 are provided in the zip file
Files
LayerFormationCode.zip
Files
(10.0 kB)
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Additional details
Funding
- Modelling dementia progression based on machine learning and simulations MR/T004347/1
- UK Research and Innovation
- Synthetic Portabolomics: Leading the way at the crossroads of the Digital and the Bio Economies EP/N031962/1
- UK Research and Innovation
- Modelling Human Brain Development EP/K026992/1
- UK Research and Innovation
- Innovation Fellowship: Computational modelling of cryopreservation of biological tissue EP/S001433/1
- UK Research and Innovation
- Computational modeling of retinal development MR/N015037/1
- UK Research and Innovation
- Controlling Abnormal Network Dynamics with Optogenetics (CANDO) NS/A000026/1
- UK Research and Innovation