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BNT162b2 Vaccine: possible codons misreading, errors in protein synthesis and alternative splicing's anomalies

Smith, Kira

The BioNTech/Pfizer BNT162b2 vaccine against Covid-19 is composed of an RNA having 4284 nucleotides, divided into 6 sections, which bring the information to create a factory of S Spike proteins, the ones used by Sars-CoV-2 (Covid-19) to infect the subject. After that, these proteins are directed outside the cell, triggering the immune reaction and antibody production.

The problem is the heavy alteration of the mRNA: the U of Uracil is replaced with Ψ (Psi) to fool the immune system and avoid degradation, the letters of all codon triplets are replaced by a C or a G, to extremely increase the speed of protein production, replacement of some amino acids with Proline, the addition of a not clear sequence (3'-UTR), combined with anomalies of alternative splicing, which is the possibility of errors in translation of the sequence and protein synthesis; they are not produced equal, but slightly different.

All this can be the cause of many inherited diseases and various types of tumors, from appearance to their growth, up to the metastasis formation.
In essence, what will be created is anything but well defined as protein S Spike: just a transcription error, wrong production of amino acids, then proteins, to cause serious long-term damage to human health, despite the DNA is not modified, being instead in the cell nucleus and not in the cytoplasm, where the modified mRNA arrives.

However, in this case, the correlation between speed of synthesis and protein expression with synthesis errors, as well as the mechanism that could affect the translation of the sequence remain obscure, as many trials are owned by BioNTech/Pfizer.

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