Journal article Open Access

ALLERGIC DISEASE REACTIONS AND DIABETIC MELLITUS: OBSERVATIONAL STUDY

Wejdan Mubarak Aldrees – Mohammed Albargi

Background and Aims:

Type 1 diabetic mellitus it is an auto immune disorder mediated by Th1 lymphocytes which beta cells of pancreases was destroyed. Only about 5% of people with diabetes have type 1 and its common in whites more than African- American. Allergic disease is a hypersensitivity conditions of the immune system from the environment that usually causes minor or no problem in most people. These hypersensitivity diseases include hay fever, food allergies, atopic dermatitis and allergic asthma. We have four types of hypersensitivity; allergic diseases are characterized by Th2 mediated immune response. 

The aim of this research is to assess the association between allergic disease (rhinitis , asthma , dermatitis) and type 1 and 2 diabetes mellitus in al-ahsa region in Saudi Arabia and collect the cases that have this relationship to be as a basis for further researches.

Methodology

Cross sectional study was conducted on both gender male and female in al-Ahsaa region in kingdom of Saudi Arabia by doing a questionnaire that include questions about both diseases. For example, we asked if they get the both diseases or not. Also, we will be fixed other factors that may affect the result like population and the time of study. At first, we collected the information on SPSS version 2020 manually to figure out the relationship.

Results:

we take 221 sample most of them where female with (66%), half of them were married, (47%) were single, and the rest widowed / divorced. The average age among them is somewhat large, ranging between (15, 50). The prevalence of allergic disease in this sample is 24 % while prevalence of diabetic mellitus type 1 is 11 %. Initial observations view that sufferers of diabetes mellitus (T1DM), were under lower risk of acquiring atopic diseases such as allergic rhinitis or asthma.

Conclusion:

our review view that patients who sufferer of diabetes mellitus (T1DM), were under lower risk of acquiring atopic diseases such as allergic rhinitis or asthma. In practical terms, this may translate into an inverse association between these two groups of diseases but the connection was not strong enough to be deemed statistically significant. While the both types of disease mostly will affect in patients the rest of their lives.   Therefore, more investigations should be done. Future studies should include more studies that deal allergic disease reactions and diabetic mellitus.

Keywords:  type 1 diabetes, atopic eczema, asthma, hay fever, allergy, food allergy , hypersensitivity.

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