Published September 30, 2020 | Version v1
Journal article Open

VOMITING OF FIRST PREGNANCY TRIMESTER: HOW TO ESTIMATE?

Creators

  • 1. Bogomolets National Medical University, Kyiv

Description

Objective of the study: to study changes of electrolyte balance and hematocrit in the first trimester vomiting and in uncomplicated pregnancy.

Material and methods. 109 women in the first trimester of pregnancy were divided into 2 groups. Group I consisted of 58 patients with complaints on vomiting from 1 to 10 times a day, group II – 51 women without complaints of nausea and vomiting. At the beginning of the study and at 20 weeks the concentrations of the main electrolytes in the serum, as well as the hematocrit index, were determined in all study participants. Groups were compared basing not only modern concentration level, but also distribution of each meaning in total.

Results. Despite the loss of fluid and electrolytes with vomiting, patients in group I did not differ from women with uncomplicated pregnancy in average ion concentrations and hematocrit. However, the distribution of the study participants by the indicators showed that the majority of women in group II had high levels of serum sodium and hematocrit. In addition, the dynamics of pregnancy progression in women of group I showed a decrease in sodium concentration and in pregnant women in group II – on the contrary, the tendency to increase this indicator.

Conclusion. Vomiting of the first trimester does not lead to significant changes in electrolyte balance. However, with the progression of pregnancy, such patients show adequate hemodilution, which implies a decrease in sodium concentration and hematocrit. At the same time, in some patients with uncomplicated course of the first trimester of pregnancy, there is a tendency for defective hemodilution. This can lead to endothelial dysfunction and associated obstetric complications, by the time patients with first pregnancy vomiting have more favorable changes of blood circulation

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