Experimental research of garden spinach extract as a potential anabolic medicinal product
- 1. Uzhhorod National University, Uzhhorod, Ukraine
- 2. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
Description
Disorders of protein metabolism – one of the pathologies, the treatment of which is an urgent problem of modern medicine and pharmacy. The importance of the problem is stipulated due to the prevalence of diseases that are accompanied by a violation of protein metabolism in the body. Restoration of protein resources during such conditions requires adequate intake of structural components from the outside – proteins, amino acids and other biologically active substances-correctors of protein metabolism. In recent decades, much attention has been paid to the discoveries of anabolic agents of natural origin, especially from plants. We conducted research on the study of the anabolic and antioxidant properties of dry extract of spinach garden leaves on the model of food deprivation in rats. Established, that the dry extract at the dose of 100 mg/kg body weight of animals prevents the development of organic disorders of protein metabolism, oxidative stress, prevents a sharp decrease in body weight and slows down the generalized catabolism caused by starvation in rats. Under the influence of the extract on the model of food deprivation, the diuretic function of the kidneys is preserved at the physiological level.
Files
PHAR_article_56880.pdf
Files
(486.3 kB)
Name | Size | Download all |
---|---|---|
md5:3ae667d4a2fd37ce0628bdd35e26081d
|
431.6 kB | Preview Download |
md5:1ac34ad105cd38396e60cf4c204f8666
|
54.8 kB | Preview Download |
Additional details
Related works
- Has part
- Figure: 10.3897/pharmacia.67.e56880.figure1 (DOI)
- Figure: 10.3897/pharmacia.67.e56880.figure2 (DOI)