Clinicopathological Correlation of CNS Tumours

Central nervous system (CNS) tumours constitute 1-2% of all neoplasms. They represent the second most common and overall the most common solid tumour of paediatric age group. Approximately 25% of all cancer related mortalities in paediatric population can occur because of CNS tumours. Aim of the study to determine the incidence of various CNS tumours and correlate histopathological diagnosis with clinical diagnosis and frozen section in selective cases. This is a retrospective and prospective study evaluating 60 patients of CNS tumours in a tertiary level hospital in Navi Mumbai. Fresh specimens obtained in intraoperative cases and postoperatively in fixative were examined and stained. Study of clinicopathological correlation gives the idea of distribution of brain tumour and demonstrates the changes in tumour spectrum in our population. High accuracy in frozen section diagnosis and its use can help in therapeutic approach which results in reduction in mortality and morbidity.