GERIATRIC PHARMACOLOGY: OVERVIEW

Global population ageing is an important challenge and opportunity to be taken virtually by all the countries. Ageing is associated with progressive decline in physiological functions as well as cluster of diseases, which alter the pharmacological response to a drug. In advanced age, the pharmacokinetics and pharmacodynamics of many drugs are altered. In addition, pharmacotherapy may be complicated by difficulties with obtaining drugs or complying with drug regimens. Safe and effective pharmacotherapy remains one of the greatest challenges in geriatric medicine. This review deals with the principles of geriatric pharmacology.