RATE OF OCCURRENCE OF IMPAIRED FASTING GLUCOSE IN 1ST DEGREE RELATIVES OF THE PATIENTS SUFFERING FROM TYPE-2 DIABETES MELLITUS AND ITS CORRELATION WITH BMI

Objectives: The aim of this study is to find out the rate of occurrence of impaired fasting glucose in the 1^stdegree relatives of the patients suffering from Type-2 DM (Diabetes Mellitus) and its correlation with BMI (Body Mass Index).

Methodology: This transverse research work was carried out at DHQ Hospital Faisalabad from August 2019 to February 2020. People with ≥ thirty-five years of age, 1^st degree relatives of the patients suffering from Type-2 DM, got recruitment in this research work and we checked their levels of FBS 2 times a week apart. We divided the participants of this research work into three groups. Group-1comprised the persons with normal fasting blood glucose (FBS: <100.0mg/dl), Group-2 contained the patients with impaired fasting glucose (100.0-125.0 mg/dl), thought to be with high risk and Group-3 contained the patients who turned out to be present with frank diabetes (FBS: ≥126.0mg/dl). The patients with known DM and having pregnancy were not included in this research work. We used the Chi square method for the comparison of the proportions of levels of impaired fasting glucose versus body mass index. P value of <0.0010 considered as significant.

Results: A sum of total one hundred patients got inclusion in this research work with average age of 44.27 years. Total 60.0% patients were present with normal FBS, 31.0% patients appeared with impaired FBS and nine percent patients were present with frank diabetes (P <0.0010). There was a significant correlation between impaired fasting glucose and body mass index. There was increase in the rate of occurrence of impaired fasting glucose with the increase in body mass index.

Conclusion: 1^st degree relatives of persons suffering from Type-2 DM showed high rate of occurrence of impaired fasting glucose and most important risk factor was obesity.

KEYWORDS: Fasting Glucose, Impaired, Body Mass Index, Occurrence, Type-2 DM, Pregnancy.