TO DETERMINE THE VARIOUS MODES OF PRESENTATIONS OF MULTIPLE SCLEROSIS

Objective: To describe different modes of presentation of multiple sclerosis in the Pakistani population and to demonstrate that multiple sclerosis may present with a wide variety of signs and symptoms.

Place and Duration: In the medical and neurological department of Khyber Teaching Hospital, Peshawar for one year duration from September 2018 to August 2019.

Methods: This one-time observational study was conducted in the neurology and medical services of the Khyber Teaching Hospital, Peshawar for one year duration from September 2018 to August 2019. Patients and their families were selected according to relevant interview samples. The data was collected in a specially designed form. 30 patients were included in the study. All patients were evaluated by clinical examination, blood tests, CSF and magnetic resonance imaging. Data were analyzed using SPSS version 18.

Results: The average age was 29.43. About 57% of patients were women. Only 16% of patients reported for the first time, while the rest had a history of previous attacks. Most patients had more than one symptom on admission. Visual disturbances, alone or with other symptoms, occurred in approximately 63% of patients. 80% of patients were weaker. Urinary incontinence occurred in 40% of patients. Cerebellar results were found in 17% of patients. In 13% of patients, multiple sclerosis is manifested by paraesthesias.

Conclusion: It has been proven that relapses can be delayed by early treatment. In addition, if neurological symptoms cannot be explained by another neurological disease, multiple sclerosis must be consider consider in differential diagnosis.

Keyword: multiple sclerosis, presentation, multiple sclerosis