Journal article Open Access

The Neuropathic Pain in Animals

Bogdan Feliks Kania*; Urszula Bracha

AbstractNeuropathic pain is serious therapeutic problem. Current therapy is often ineffective and the available drugs have serious side ef-fects. For these reasons, the search for alternative therapeutic solutions is underway. Recent research on metabotropic receptors for glutamic acid (mGluR) gives great hope for the development of a new type of drug in the treatment of neuropathic pain. Particularly promising are antagonists of mGluR group I receptors. There are numerous studies demonstrating the efficacy of non-competitive mGlu1 and mGlu5 receptor antagonists in animal models of neuropathic pain. The purpose of this review article is to gather informa-tion obtained from research on the role of mGluR antagonists in neuropathic pain.

Files (499.1 kB)
Name Size
499.1 kB Download
All versions This version
Views 88
Downloads 44
Data volume 2.0 MB2.0 MB
Unique views 88
Unique downloads 33


Cite as