Journal article Open Access

The Neuropathic Pain in Animals

Bogdan Feliks Kania*; Urszula Bracha

AbstractNeuropathic pain is serious therapeutic problem. Current therapy is often ineffective and the available drugs have serious side ef-fects. For these reasons, the search for alternative therapeutic solutions is underway. Recent research on metabotropic receptors for glutamic acid (mGluR) gives great hope for the development of a new type of drug in the treatment of neuropathic pain. Particularly promising are antagonists of mGluR group I receptors. There are numerous studies demonstrating the efficacy of non-competitive mGlu1 and mGlu5 receptor antagonists in animal models of neuropathic pain. The purpose of this review article is to gather informa-tion obtained from research on the role of mGluR antagonists in neuropathic pain.

Files (499.1 kB)
Name Size
AVAS-02-0016.pdf
md5:665c381500dc468c4c3bbf3d7ad51c93
499.1 kB Download
8
4
views
downloads
All versions This version
Views 88
Downloads 44
Data volume 2.0 MB2.0 MB
Unique views 88
Unique downloads 33

Share

Cite as