FREQUENCY OF DIASTOLIC DYSFUNCTION IN CASES OF DIABETES MELLITUS

Objective: Frequency of diastolic dysfunction in cases of Diabetes Mellitus. Methodology; This cross-sectional study was conducted during July 2019 to December 2019 at department of cardiology and Medicine. Hundred cases of diabetes mellitus of both gender i.e. male/female with age more than 40 years and duration of DM of at least 2 years and of type II DM were included. The cases with previous history of acute coronary syndrome, valvular disease, liver or renal disease were excluded. The cases were labelled as Diastolic dysfunction where E/A ratio was <0.8 assessed on transthoracic echocardiography. Results; In this study, out of 100cases there were 61 (61%) males and 39 (39%) females with mean age of 54.34±9.41 years. There were 36 (36%) cases had HTN. Diastolic dysfunction was observed in 49 (49%) of cases. There was no significant difference in terms of gender in both groups with p= 0.79. Diastolic dysfunction was more in cases that had HTN where it was seen in 25 (69.44%) of cases with p= 0.001. There was significant difference in cases that had BMI more than 30 where it was seen in 30 (62.50%) of cases with p= 0.001.

Conclusion: Diastolic dysfunction is seen in almost half of the cases with DM and it is significantly high in cases that had HTN and BMI more than 30.

Key words: Diastolic dysfunction, Diabetes Mellitus