Report Open Access
Philip Doganis, Bengt Fadeel, Roland Grafström, Janna Hastings, Markus Hegi, Nina Jeliazkova, Vedrin Jeliazkov, Cristian Munteanu, Haralambos Sarimveis, Bart Smeets, Georgia Tsiliki, David Vorgrimmler, Egon Willighagen, Barry Hardy
We reviewed the current state of the art of availability and requirements for nanomaterial databases, through reviewing the literature, online resources, engaging in discussions with the NanoSafety Cluster working groups and using the results of a community-based requirement analysis. The eNanoMapper data architecture was developed and consists of a set of web services, providing access to experimental protocols and data, search service and modules, facilitating linking and data transfer between third party databases. This design is expected to facilitate adding new services of any kind, for example supporting different data types and data analysis. The technical solution is able to support the required data types, queries, and annotations, and can enable user friendly applications. The resulting eNanoMapper data access architecture was developed based on the OpenTox framework and Application Programming Interfaces and extensions to them. An eNanoMapper prototype supporting the inclusion of data and protocols was developed and deployed, based on a number of public datasets relevant to Nano Safety.