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Published April 9, 2020 | Version v1
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Expansion of UBTR012574 Chemical Series Pt. II

  • 1. University of Toronto, Structural Genomics Consortium

Description

Docking analogues of UBTR012574 against the USP5 zinc finger ubiquitin-binding domain (ZnF-UBD) to prioritize compound synthesis.

Notes

Funding acknowledgement: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome

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1_Expansion of UBTR012574 chemical series pt 2.pdf

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