Published January 21, 2020
| Version v1
Dataset
Open
USP5 ZnF-UBD Co-Crystal Structure with Compound UBTR012574a
- 1. University of Toronto, Structural Genomics Consortium
Description
Objective: To grow well-diffracting co-crystals of USP5 zinc finger ubiquitin binding domain (ZnF-UBD) to solve the co-crystal structures to determine ligand interactions in the binding pocket and to determine if the predicted binding pose is similar to the experimental binding pose.
Notes
Funding acknowledgement: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.
Files
1_USP5 ZnFUBD and compound UBTR012574a co-crystal structure.pdf
Files
(2.0 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:ba84ab8a3a020d220888323e1a991329
|
366.3 kB | Preview Download |
|
md5:6641b351ffe35b5b24acc99d4e7f3405
|
29.2 kB | Download |
|
md5:18dbfbb81d615ad993de0ae0533b02bd
|
6.5 kB | Download |
|
md5:937bff855174e374f19b578585fde94a
|
169.5 kB | Download |
|
md5:2b1278b2c1d5ded6786bce0d8824a330
|
1.4 MB | Download |