Serum calcium levels, serum magnesium levels and calcium magnesium ratios in different phases of menstrual cycle

Female reproductive hormone changes in the menstrual cycle affect the mineral metabolisms which in turn cause disorders in the body. This study was aimed at evaluating serum calcium, magnesium, and Ca:Mg ratio during the follicular, ovulatory and luteal phase in 80 women (15 - 45 years). The detailed menstrual history including basal body temperature for two consecutive cycles were recorded. The ovulation day was estimated individually from the change in basal body temperature and the phases were estimated from the individual cycle length and estimated ovulation day. The follicular, ovulatory and luteal phase blood samples were taken during Day 8 - 10, Day 14 - 16 and Day 22 - 26 respectively. The concentrations of calcium and magnesium were estimated by colorimetric method.