Antigen and antibody for Coronavirus RNA Vaccination Development

Coronavirus and its strains are associated to the subfamily of Orthocoronavirinae. It is associated with the family of Coronaviridae and order of Nidovirales and realm in Ribavirin. These are enveloped viruses with positive single stranded RNA genome and nucleocapsid of helical symmetry. The size of genome for coronaviruses varies from 27 to 34 kilobases.
Mutation of Coronavirus may or may not be recognized by the immune system on subsequent infection; and once it highjacks host of the cell, replication of virus becomes faster. As a result immune system will be unable to recognize the strains of these infections; infections caused by coronavirus like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) have inclined to be very severe and can cause significant mortality. In this paper discusses about antigen and antibody for development of vaccines for coronavirus and its strains so that some of the B cells become memory B cells which recognizes future exposure to the disease.