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Published March 31, 2020 | Version 1.0
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Statistical review of Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial

  • 1. Centre for Biostatistics, Manchester Academic Health Science Centre, University of Manchester.
  • 2. HRB Clinical Research Facility - Cork. HRB Trial Methodology Research Network. University College Cork School of Public Health

Description

The following review has been prepared in collaboration with members of the MRC-NIHR Trials Methodology Research Partnership. The reviewers named above, and other, unnamed discussants of the paper, are all qualified statisticians with experience in clinical trials. Our objective is to provide a rapid review of publications, preprints and protocols from clinical trials of COVID-19 treatments, independent of journal specific review processes. We aim to provide timely, constructive, focused, clear advice aimed at improving both the research outputs under review, as well as future studies. Given our collective expertise (clinical trial statistics) our reviews focus on the designs of the trials and other statistical content (methods, presentation and accuracy of results, inferences). Here we review Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial, by Chen et al. https://www.medrxiv.org/content/10.1101/2020.03.17.20037432v2

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Preprint: 10.1101/2020.03.17.20037432 (DOI)