Tables S2-S3. SMR-HEIDI results for 8q24.21 locus between back pain and other phenotypes.
Creators
- 1. Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom
- 2. aboratory of Theoretical and Applied Functional Genomics, Novosibirsk State University, Novosibirsk, Russia; Laboratory of Recombination and Segregation Analysis, Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia
- 3. Department of Molecular and Biological Physics, Moscow Institute of Physics and Technology (State University), Moscow, Russia; LResearch and Training Center on Bioinformatics, A.A. Kharkevich Institute for Information Transmission Problems, RAS, Moscow, Russiaaboratory of Theoretical and Applied Functional Genomics, Novosibirsk State University, Novosibirsk, Russia;
- 4. Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington, United States of America; Division of Rehabilitation Care Services, VA Puget Sound Health Care System, Seattle, Washington, United States of America
- 5. Laboratory of Recombination and Segregation Analysis, Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia; Polyomica, 's-Hertogenbosch, the Netherlands
Description
Supplementary Table S2. SMR-HEIDI results for 8q24.21 locus between back pain and other complex traits.
Column headers of Tables S2:
Secondary Trait Name: Name of complex trait
Dataset: Name of dataset (UKB Neale's lab or UKB Gene Atlas)
Index_SNP: RsID of SNP used as target in SMR-HEID analysis
Proxy_SNP: RsID of top SNP in the selected locus - SNP presented in both GWAS data with minimum P-values in back pain GWAS
r(proxy_SNP,index_SNP): linkage disequilibrium coefficient between index and proxy SNP
beta_SMR: Beta SMR for proxy SNP
p_SMR: P-value of beta SMR
qFDR-BH SMR: P-value of beta SMR after Bonferroni correction
p_HEIDI: P-value of HEIDI test
n_HEIDI: Number of SNPs used in HEIDI test
SNPs_HEIDI: List of rsID of SNPs used in HEIDI test
Supplementary Table S3. SMR-HEIDI results for 8q24.21 locus between back pain and expression of genes.
Column headers of Tables S3:
Secondary Trait Name: Name of complex trait
Tissue: Name of the tissue from which the samples were taken to study gene expression
Gene_name: Gene name corresponding to the transcript name
Transcript Name: Transcript name (ID)
Dataset: Name of dataset (CEDAR, GTEx_v6)
beta_SMR: Beta SMR for proxy SNP
p_SMR: P-value of beta SMR
qFDR-BH SMR: P-value of beta SMR after Bonferroni correction
p_HEIDI: P-value of HEIDI test
n_HEIDI: Number of SNPs used in HEIDI test
SNPs_HEIDI: List of rsID of SNPs used in HEIDI test
Part of the article: Williams FMK et al. "Sequence variation at 8q24.21 and risk of back pain"
Files
SMR-HEIDI results ST2.csv
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Additional details
Related works
- Is continued by
- Dataset: 10.5281/zenodo.3715005 (DOI)