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SmaragdaT/GenEpi V1.0

SmaragdaT

Package for calculating response to genetic selection for lower susceptibility and/or infectivity following standard quantitative genetics theory assuming polygenic genetic variation, and then simulating epidemics on the selected populations following a stochastic SIR (Susceptible, Infected, Recovered) epidemiological model, to evaluate the change in epidemic severity and risk due to selection over generations.

S. Tsairidou, O. Anacleto, J.A. Woolliams, A. Doeschl-Wilson. 2019. Enhancing genetic disease control by selecting for lower host infectivity and susceptibility. Heredity. https://doi.org/10.1038/s41437-018-0176-9

Keywords: genetic selection, epidemiological modelling, infectious disease, simulation, breeding for disease resistance, genetic disease control

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