METHOD DEVELOPMENT AND STATISTICAL VALIDATION OF VALSARTAN IN BULK AND TABLET DOSAGE FORM BY UV SPECTROPHOTOMETRIC METHOD

A simple, accurate, specific and precise UV Spectrophotometric method has been developed for estimation of Valsartan in bulk and pharmaceutical formulation. The λ max of Valsartan in ethanol was found to be 249 nm. The drug exhibited the linearity in the concentration range of 10-60μg/mL with correlation coefficient of 0.999. the % recovery of the drug for the proposed was found to be between 99.82 to 100.48%. The % RSD values found to be less than 2. No interference was observed in the presence of common pharmaceutical excipients. The method was validated as per ICH guidelines. The developed method was successfully employed for the estimation of Valsartan in pharmaceutical dosage form. The developed method was cost effective with less consumption of solvents and can be used for routine analysis.