Published October 24, 2019 | Version v1
Dataset Open

Do ZnF-UBD ligands bind full length USP5?

Creators

  • 1. University of Toronto, Structural Genomics Consortium

Description

A surface plasmon resonance (SPR) assay was used to determine the binding affinities of USP5 zinc finger ubiquitin-binding domain (ZnF-UBD) ligands to full length (FL) USP51-835

Notes

Funding acknowledgement: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.

Files

1_20191024 SPR FL USP5.pdf

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