Published July 23, 2019 | Version pre-final
Conference paper Open

A comparison of three multimodality coronary 3D reconstruction methods

  • 1. Unit of Medical Technology and Intelligent Information Systems, Dept. of Materials Science and Engineering, University of Ioannina, Greece
  • 2. Dept. of Biomedical Research, FORTH-IMBB, Greece
  • 3. Dept. of Interventional Cardiology at the Heart Institute (InCor) University of Sao Paulo Medical School
  • 4. Michaelideion Cardiac Center, Dept. of Cardiology in Medical School, University of Ioannina, Greece

Description

The assessment of the severity of arterial stenoses is of utmost importance in clinical practice. Several image modalities invasive and non-invasive are nowadays available and can be utilized for the 3-dimensional (3D) reconstruction of the arterial geometry. Following our previous study, the present study was conducted to further strengthen the evaluation of three reconstruction methodologies, namely: (i) the Quantitative Coronary Analysis (QCA), (ii) the Virtual Histology Intravascular Ultrasound VH-IVUS-Angiography hybrid method and (iii) the Coronary Computed Tomography Angiography (CCTA). Data from 13 patients were employed to perform a quantitative analysis using specific metrics, such as, the Mean Wall Shear Stress (mWSS), the Minimum Lumen diameter (MLD), the Reference Vessel Diameter (RVD), the Degree of stenosis (DS%), and the Lesion length (LL). A high correlation was observed for the mWSS metric between the three reconstruction methods, especially between the QCA and CCTA (r=0.974, P<0.001).

Notes

This is a pre-final version of the manuscript published in 41st International Engineering in Medicine and Biology Conference (EMBC), Berlin, Germany. For the citation of the paper please use the DOI from the conference proceedings.

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Funding

European Commission
SMARTool – Simulation Modeling of coronary ARTery disease: a tool for clinical decision support 689068