MANAGEMENT AND PROGNOSTIC FACTORS OF SQUAMOUS CELL CARCINOMA AND ADENOCARCINOMA OF THE UTERINE CERVIX

Aim:To investigate the clinicopathological characteristics and survival of squamous cell carcinoma and adenocarcinoma the cervix using Surveillance, Epidemiology, and end Results database. Method:Patients with a diagnosis of squamous cell carcinoma and adenocarcinoma of the cervix were included between 2014 and 2019. Kaplan-Meier method and Cox regression models were used. Result: A total of 186 patients were included in this studyof which patients with known International Federation of Gynecology and Obstetrics stage and tumor grade, the stage III disease was diagnosed in 9.6% patients, and 26.46% patients had poorly or undifferentiated histology and well differentiated are 67.72%. The cumulative 5-year survival rates for stages Ib, II, and III/IVa disease were 93.5, 77.0, and 60.3%, respectively. Conclusion: In multivariate analysis, the survival outcome of the patients remained high in the study that is mostly due to more patients of primary stages also the survival is associated with age. Squamous cell carcinoma is common and has aggressive characteristics, prone to metastasize and is dismal in prognosis compere to adenocarcinoma of the cervix.

Keywords: Uterine cervical neoplasm, cervical cancer staging, hysterectomy, prognosis.