Cancer therapy using microorganism

The rising incidence of cancer generates a need of novel treatment options. Applying biological agents may represent a valuable therapeutic variant that is intensively investigated nowadays. For example, some bacteria in addition to their intrinsic antitumor effect can be used as vector systems that shuttle therapeutic compounds into the tumor. Also we can design recombinant vaccines by employing the BPV viruses against HPV (the agent of cervical cancer), the second most fatal cancer in women. Strategic solutions like these are optimal usage of biological agents that may overcome limitations of conventional therapies. Despite intensive research as well as improved classical and newly developed therapies, cancer remains the second cause of death in industrialized societies. Common therapies like surgery, radiotherapy, or chemotherapy remain the main of cancer therapy to date. However, not every cancerous tissue can be pointed with a scalpel and physical and chemical methods in general do not distinguish between healthy and malignant tissue. Researches revealed cancer as a highly complex and multifactorial type of disease. The aim of presenting this article is perusing the studies on microorganisms to achieve long lasting antitumor effects that pursue it since the past.