Have IgE and IgG4 antibodies become vaccine injury biomarkers?

IgE and IgG4 are naturally involved in defense against helminth and parasite infections. Injected antigens result in IgE synthesis. Vaccines contain numerous proteins including food proteins, fungal proteins, animal proteins and aeroallergens. The result is IgE synthesis against all these antigens. Continued exposure to these antigens results in IgG4 synthesis. IgE and IgG4 result in numerous diseases such as food allergies, asthma, autism, eosinophilic esophagitis, membranous nephropathy, type 1 diabetes etc. Since in developed countries parasite infections are rare, parasite directed IgE/IgG4 are also rare. Therefore in developed countries, IgE/IgG4 are likely to be reliable vaccine injury biomarkers.