Journal article Open Access

NARRATIVE REVIEW ON INSIGHTS OF OPTHALMIC DRUG DELIVERY BY USING CONTACT LENSES

A. DEEVAN PAUL*, N. ALEKYA, N. ROOPA, NAVYAJA KOTA, NIRANJAN RAO PODILI

In ocular drug delivery system (ODDS) majority of medications are delivered as eye drops and these may reduce the intraocular pressure but having major deficiencies like low patient compliance and low bioavailability. Therefore, ophthalmic drug delivery has become very fashionable with their distinctive benefits like extended drug release and more than 50% bioavailability. To achieve controlled and sustained drug deliveries from contact lenses, we tend to come that numerous techniques like compounding into nanoparticles, micelle, liposomes have many technologies in developing the load of a drug connected lenses like soaking, molecular acquisition, defense of drug loaded mixture nanoparticles, ion ligand polymeric system. Some of the major disadvantages to this technology are corneal problems, conjunctivitis etc. The rate of drug delivery is not constant overtime with the bulk of medicine within the lens being delivered within the initial stage rather that at end of treatment period.

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