INCREASED EFFECTIVENE USEFULNESS OF DILATATION WITH INTRALESIONAL STEROID INJECTIONS IN CORROSIVE OESOPHAGEAL STRICTURES TREATMENT

Objectives: The research objective is the comparison of the effectiveness of intralesional steroid injection with dilatation VS with dilatation only while treating corrosive oesophageal strictures.

Method: We conducted this randomized controlled trial at Services Hospital, Lahore (October 2017 to November 2018). We took 60 patients (15 – 50) years’ age having either gender and divided them into two groups; Group-A and Group-B using lottery method. We performed endoscopic dilatation in Group-A and Intra-lesional Triamcinolone injection with dilatation in Group-B. We followed-up the endoscopic dilatation for every 02 weeks. Using SPSS software, we analyzed the collected data.

Results: We took 60 patients, dividing into two groups, each consisting of an equal number (30 or 50%) of patients. We recorded the overall mean age as (32.6 ± 10.6) years among all patients with (1.7:1) of male to female ratio. The mean stricture length at baseline of Group-A (dilatation) and Group-B (combination) was (23.3 ± 2.2 cm) and (24.2 ± 3 cm) respectively. The mean length of stricture in Group-A and Group-B was (11.2 ± 3 cm) and (5.33 ± 3 cm) respectively with (P-value = 0.0001).

Conclusion: The combination group (Oesophageal + dilatation) was more effective comparing to dilatation only group.

Keywords: Intra-lesional Steroid Injection (ILSI), Corrosive Oesophageal Strictures (COS), Stricture Length (SL), and Oesophageal Strictures (OS).