Published March 17, 2019 | Version v1
Journal article Open

PATHOMORPHOLOGICAL CHANGES IN NEWBORN PIGS INDUCED BY INFECTION WITH VACCINAL STRAINS AND FIELD ISOLATES OF SUID HERPES VIRUS 1. PART II. RESPIRATORY SYSTEM

Creators

  • 1. University of Forestry, Faculty of Veterinary Medicine, Sofia, Bulgaria

Contributors

  • 1. University of Forestry, Bulgaria

Description

Comparative pathomorphological studies of newborn piglets prior to colostrum intake after infec-tion with a vaccine strain and two uterothropic strains of the Aujeszky's disease strains – Mogila and Zagora II were performed. The studies were conducted with 21 large, well-developed piglets derived from an industrial pig farm, without antibodies to Suid herpesvirus 1. Histological, histochemical and electron microscopic studies have been performed. It was found that strains of the Aujeszky's disease, which differ in virulence and tissue tropism, caused different severity, characteristic clinical signs and pathomorphologic changes in experimental animals. The clinical signs are related to changes in the respir-atory and digestive systems, bedsores and apathy. In the lungs of the pigs, infected with strain St. Zagora II and strain MK 35gE-, atelectatic and proliferative changes were observed. Serous – fibrinous pleuritis, fibrinogen necrotic pneumonia and the presence of inclusions type Cowdry A in the epithelial and con-nective tissue in lungs of the tested animals were inspected.

Files

vol-4-1_2019-14-19.pdf

Files (233.8 kB)

Name Size Download all
md5:f5f2fc739defbaca28442dc0193f52fe
233.8 kB Preview Download

Additional details

Related works

Is documented by
http://scij-tmvm.com/vol./vol.4/1/vol-4-1_2019-14-19.pdf (URL)

References

  • Christensen, L. S., Motovski A. (1993). Molecular epizootological studies of Bulgarian isolates of Augeszky disease virus. Eight Congress of the Microbiologist in Bulgaria, 21–23 October 1993, Varna, 7/602.
  • Dee, SA. (2016). Overview of pseudorabies. In: IKahn CM, Line S, Aiello SE, editors. The Merck veterinary manual [online]. Whitehouse Station, NJ: Merck and Co; Available at: http//www.merckvetmanual. com/nervoussystem/pseudorabies/overview-of-pseudorabies.
  • Ducatelle, R., Coussement W., Hoorens J. (1982). Immunoperoxidase study of Aujeszky`s disease in pigs. Res. Vet. Sci. 32, 3, 294–302.
  • Dyakov, L., Lozanov L., Angelov A., Stoykov D. Practicum in Veterinary Medicine Pathology. Zemizdat, Sofia, 1989.
  • Klimke, A. (1991). Diagnosis of Aujeszky`s disease in pigs: analgsis of case records, histological findings and immunochisological findings, I nahgural. Dissertation, Tierozztliche Hochschule, Hanover, Germany.
  • Motovski, A., Peev Y., Dyakov I., Florova I. (1991). Studies on the role of the Aujeszky's disease virus in porcine reproductive disorders. Jubilee Scientific Session on the 90th Anniversary of CRVMI, Sofia, 14–20 IX 1991.
  • Narita, M., Imada T., Haritani M. (1990). Comparative pathology of HPCD pigs infected with wild type and ara-T-resistant strains of Aujeszky`s disease virus. J. Comp. Phatol., 102, 1, 63–69.
  • Narita, M., Kawashima K., Matsuura S., Uchimura A., Miura Y. (1993). Pneumonia in pigs inoculated with pseudorabies virus by means of a bronchoscope. J. Comp. Pathol., 109, 4, 335–344.
  • Nauwynck, H., Pensaert M. (1994). Interactions of Aujeszky`s disease virus and porcine blood mononuclear cells in vivo and in vitro. Acta. Vet. Hung., 42, 2–3, 301–308.
  • Shibata, I., Yazawa S., Ono M., Okuda Y. (2003). Experimental dual infection of specific pathogenfree pigs with porcine reproductive and respiratory syndrome virus and pseudorabies virus. J. Vet. Med. B. Infect. Dis. Vet. Public. Health. 50, 1, 14–19.
  • Vannier, P. (1987). Le virus de la maladie D`Aujeszky et les affecions respiratoires du Porc. Rec. Med.Vet., 163, 4, 407–417.
  • Veselinova, A. (1982). Pathomorphological, cytological and immunomorphological studies of Aujeszky's disease in pigs. Doctor's thesis, C. 1–366.