STUDY OF THE INFLUENCE OF L-NORVALINE, ROSUVASTATIN AND THEIR COMBINATION ON THE LEVEL OF MICROCIRCULATION IN BONE TISSUE IN EXPERIMENTAL OSTEOPOROSIS AND FRACTURES ON ITS BACKGROUND

The experiment was carried out in female white Wistar rats to investigate the effect of L-norvaline, rosuvastatin and their combination on parameters of blood supply to the bone tissue on models of experimental osteoporosis and osteoporotic fractures. It was found that the studied drugs prevent reduction of microcirculation in osteoporotic bone tissue as well as in callus tissue of experimental osteoporotic fractures and it positively influences the course of reparative regeneration of bone tissue.