Published January 5, 2019
| Version v1
Journal article
Open
EuroMix PBPK model for combined exposures
Description
In this paper documents the structure and default parameter values of the EuroMix PBPK model
implemented in the MCRA platform for rats and humans. A version allowing apportionment of
results by exposure routes is also described. Finally, the extensions needed to describe
pharmacokinetic interactions between pairs or triplets of substance are discussed.
Files
Euromix - D4.2 PBPK_coexposures.pdf
Files
(1.0 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:5c74f703470c0c9a8b25e60e67b798e3
|
1.0 MB | Preview Download |