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Published November 30, 2018 | Version v1
Journal article Open

PREVALENCE OF SECONDARY HYPERPARATHYROIDISM IN CHRONIC KIDNEY PATIENTS

  • 1. Malla Reddy Institute of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Telangana, India.

Description

Secondary hyperaparathyoidism occurs mainly due to chronic kidney disease which aggravates from stage 1-5, which is due to imbalance between calcium and phosphorous homeostasis. Secondary hyperparathyroidism is the serious issue to be considered because of its complications including cardiovascular disease soft tissue and vascular calcification calcific uremic arteriolopathy (CUA). Our study was to find the prevalence of secondary hyperparathyroidism that would help to find out the epidemiological spread of the disease that would help in improving the treatment effectiveness for the safety of the subjects. our study includes 60 subjects who are undergoing dialysis from 12 to 48 months of duration we found high prevalence of secondary hyperparathyroidism with 66.6 % patients with IPTH levels over 300pg/ml, 83% of the patients were found to be hypocalcaemia and 75% of the patients were found to be having abnormal phosphorous levels with majority having high phosphorous levels so based on our study prevalence of secondary hyperparathyroidism was high which would results in serious complications like bone dystrophy which left untreated would result to death. The final result of our study include majority of the patient have secondary hyperparathyroidism which would results in further complications like bone dystrophy and cardiovascular abnormality left untreated would result in further menacing complications which left untreated would may lead to death of the patients.

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