THYROID DISTURBANCES IN METABOLIC SYNDROME AT TERTIARY CARE HOSPITAL

Objective: To determine the thyroid disturbances in metabolic syndrome at tertiary care hospital.

Patients and Methods: The six month cross sectional study explored the patients who were diagnosed as metabolic syndrome and fulfill inclusion criteria (age ≥ 18 years, either gender who fulfilled the criteria for metabolic syndrome by IDF were taken into study) were recruited for study. The detailed history and clinical examination was performed while along the baseline investigations the specific investigation includes fasting blood sugar, fasting lipid and thyroid profile (TSH, FT4 and FT3). The disturbances were classified as euthyroidism, sub clinical hypo / hyperthyroidism, hypothyroidism and hyperthyroidism. The frequency / percentages (%) and means ±SD computed for study variables.

Results: During six months study period total fifty patients of metabolic syndrome were explored for thyroid profile. The frequency for male and female population was 30 (60%) and 20 (40%) with mean ± SD for age of male and female individuals was 42.86±6.53 and 44.41±7.62 respectively whereas the mean ± SD for systolic and diastolic blood pressure, fasting blood sugar, waist circumference, high density lipoprotein and triglycerides was 160.55±10.85 and 100.74±5.93, 172.82±10.42, 98.92±7.72, 32.86±7.95 and 243.43±10.51 respectively. Regarding gender distribution male 23 (46%) and female 27 (54%) while the thyroid dysfunction euthyroid 32 (64%), hypothyroid 05 (10%), subclinical hypothyroidism 10 (20%), subclinical hyperthyroidism 02 (4.0%) and hyperthyroidism 01 (2.0%).

Conclusion: Thyroid dysfunction is common and more prevalent in metabolic syndrome.

Keywords: Thyroid, Euthyroid, Hypothyroid and Hyperthyroidism