Published April 30, 2017 | Version v1
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ANTI-PLATELET AGGREGATION STUDY ON RASAM: A SOUTH INDIAN TRADITIONAL FUNCTIONAL FOOD

  • 1. 1Department of Pharmaceutics, Hillside College of Pharmacy & Research Centre, Bengaluru, Karnataka, India. 2Pharmacy Department, Centre for Research & Development, PRIST University, Thanjavur, Tamil Nadu, India.

Description

Rasam, is a common South Indian traditional spice soup. The ingredients used in the preparation of rasam are medicinally claimed for anti-platelet aggregation activity. Hence, rasam was studied for its anti-platelet aggregation potential beyond its culinary and nutritional effect. Adenosine diphosphate induced platelet aggregation study for four stage wise samples in the preparation of rasam (RS1, RS2, RS3 and RS4) were studied. RS4, the final product of rasam showed higher percentage of platelet aggregation inhibition and IC50 value of 93.43% and 10.75 μL/mL respectively than other samples. The percentage of platelet inhibition of rasam was found to be directly proportional to the concentration. Rasam is a traditional functional food and can be an anti-platelet aggregation inhibitor on chronic use.

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