Published January 31, 2022
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Table 2 in Polyketide-derived macrobrevins from marine macroalga-associated Bacillus amyloliquefaciens as promising antibacterial agents against pathogens causing nosocomial infections
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- 1. * & Marine Bioprospecting Section of Marine Biotechnology Division, Central Marine Fisheries Research Institute, Ernakulam North, P. B. No. 1603, Cochin, Kerala State, India
Description
Table 2 Antibacterial activities of macrobrevin analogues 1–4 and commercial standards against clinical pathogens.
| Pathogens | 1 | 2 | 3 | 4 | Chloramphenicol | Ampicillin |
|---|---|---|---|---|---|---|
| E. coli (MTCC 443) | 17b ± 0.05 (6.25) | 23 a ± 0.01 (3.12) | 29 a ± 0.05 (3.12) | 24 a ± 0.10 (6.25) | 16b ± 0.02 (6.25) | 10 c ± 0.02 (6.25) |
| V. parahaemolyticus (MTCC 451) | 21b ± 0.34 (3.12) | 26 a ± 0.05 (1.56) | 33 a ± 0.15 (1.56) | 26 a ± 0.05 (3.12) | 11 c ± 0.06 (6.25) | 12 c ± 0.01 (6.25) |
| P. aeruginosa (ATCC 27853) | 19b ± 0.03 (3.12) | 13c ± 0.20 (6.25) | 23a ± 0.25 (1.56) | 22b ± 0.02 (3.12) | 11c ± 0.02 (12.50) | 11c ± 0.04 (12.50) |
| K. pneumoniae (ATCC 13883) | 11c ± 0.04 (6.25) | 16b ± 0.05 (6.25) | 25a ± 0.02 (1.56) | 24a ± 0.06 (3.12) | 7 d ± 0.04 (12.50) | 9d ± 0.04 (12.50) |
| E. tarda (MTCC 2400) | 20b ± 0.02 (6.25) | 25 a ± 0.05 (3.12) | 27 a ± 0.03 (3.12) | 27 a ± 0.05 (3.12) | 14 c ± 0.01 (6.25) | 13 c ± 0.01 (6.25) |
| S. pyogenes (MTCC, 1924) | 22b ± 0.01 (3.12) | 21b ± 0.02 (3.12) | 30 a ± 0.01 (1.56) | 23 a ± 0.02 (6.25) | 15 c ± 0.03 (6.25) | 15 c ± 0.05 (6.25) |
| MRSA (ATCC 33592) | 20b ± 0.15 (6.25) | 22b ± 0.01 (3.12) | 24 a ± 0.10 (1.56) | 21b ± 0.01 (3.12) | 14 c ± 0.02 (6.25) | 14 c ± 0.02 (12.50) |
| VRE fs (ATCC 51299) | 22b ± 0.20 (6.25) | 24 a ± 0.04 (6.25) | 34 a ± 0.05 (1.56) | 25 a ± 0.05 (6.25) | 8d ± 0.01 (6.25) | 11 c ± 0.05 (6.25) |
Notes
Published as part of Chakraborty, Kajal, Kizhakkekalam, Vinaya Kizhakkepatt & Joy, Minju, 2022, Polyketide-derived macrobrevins from marine macroalga-associated Bacillus amyloliquefaciens as promising antibacterial agents against pathogens causing nosocomial infections, pp. 7 in Phytochemistry (112983) 193 on page 7, DOI: 10.1016/j.phytochem.2021.112983, http://zenodo.org/record/8235151
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