Published November 13, 2018 | Version 1.0
Dataset Open

Comparison and Assessment of Family- and Population-based Genotype Imputation Methods in Large Pedigrees Dataset

Creators

  • 1. Qatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar
  • 2. Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, USA
  • 3. Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, USA, Department of Biostatistics, University of Washington, Seattle, USA

Description

Here is the data corresponding to the paper "Comparison and Assessment of Family- and Population-based Genotype Imputation Methods in Large Pedigrees" submitted to Genome Research.  The data includes the following:

Simulated data for 1200 African and European subjects in pedigrees.
Lists of subjects selected by each of the 4 subject selection methods examined; Primus, GIGI-Pick, Exome-Picks, and Random selection. 

The positions of sparse markers for gl_auto for African and European data.

The lists of GWAS SNPs for AFR and EUR. 

Please see the paper for further details of the data generation, this metadata will be updated following publication. 

Notes

A great part of the computation used in the corresponding study and for generating this data was performed on the Raad2 cluster at Texas A&M University in Qatar. Partially supported by grant support from the US National Institutes of Health, R01 MH094293, R01 HD088431, R37 GM046255, R24 OD021324, and P50 AG005136.

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