Published December 12, 2014 | Version v1
Journal article Open

Needle Revision with Antimetabolites in Bleb Failure

Creators

  • 1. Ehab Ghoneim, MD, Professor of Ophthalmology, Suez Canal University, Ismailia, 6532, Egypt
  • 1. #S2, 215, Kavuri Hills Jubilee Hills, Hyderabad-500033, India

Description

Glaucoma filtering surgery is unusual in that its goal is the creation and maintenance of a non healing fistula between two anatomic spaces that are normally not connected [1]. 

Fibroblasts, connective tissue elements, cytokines, aqueous humor and the surrounding vascular supply all influence what happens to a bleb over a long period of time.

The enemy of drainage procedure is excessive scarring [2]. 

Long-term studies showed a loss of intraocular pressure (IOP) control in a significant proportion of eyes with an initially successful trabeculectomy [2,3]. So follow up of glaucoma patients after surgery is mandatory as significant proportion develop bleb failure.

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