Orthodontically Induced External Apical Root Resorption with genetic and non-genetic factors
Creators
- 1. Medical Genetics Department, Faculty of Medicine, University of Coimbra, Portugal; CIMAGO (Center of Investigation on Environmental, Genetics and Oncobiology), Faculty of Medicine, University of Coimbra, Coimbra, Portugal
- 2. Institute of Orthodontics, Faculty of Medicine, University of Coimbra, Portugal
- 3. Coimbra Polytechnic - ISEC, Coimbra, Portugal
- 4. Centro ALGORITMI, School of Engineering, University of Minho, Portugal
Description
Orthodontically Induced External Apical Root Resorption (OIEARR) dataset with genetic and non-genetic factors from a sample of 195 patients previously submitted to orthodontic treatment. Methodology for patient selection is described in published related works as well as materials and methods. Percentage of OIEARR were assessed in maxillary teeth: the four incisors and the two canines. Ten clinical and treatment variables were recorded: gender, age, treatment duration, premolar extractions, skeletal pattern, Hyrax appliance, functional appliance, overjet, anterior open bite and tongue thrust. Single nucleotide polymorphisms (SNPs) of six genes : rs114363 from IL1B; rs3102735 from TNFRSF11B, encoding OPG; rs1059703 from IRAK1; rs315952 from IL1RN; rs1805034 from TNFRSF11A, encoding RANK; rs1718119 from P2RX7.
Files
OIEARRdata.csv
Files
(23.3 kB)
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Additional details
References
- PEREIRA S, LAVADO N, NOGUEIRA L, et al. Polymorphisms of genes encoding P2X7R, IL-1B, OPG and RANK in orthodontic-induced apical root resorption. Oral Dis.2014;20:659-667.
- PEREIRA S, NOGUEIRA L, CANOVA F, et al. IRAK1 variant is protective for orthodontic-induced external apical root resorption. Oral Dis. 2016;22:658–664.