Published December 1, 2006 | Version v1
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Determination of binding constants for activating ligands of pyruvate decarboxylase from Kluyveromyces lactis using SAXS parameters

  • 1. Institute of Biochemistry & Biotechnology, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany
  • 2. European Molecular Biology Laboratory (EMBL c/o DESY), Hamburg Outstation, Germany

Description

Hasylab Ann. Rep. 2006, 319-320

This report illustrates global structural changes of the pyruvate decarboxylase from Kluyveromyces lactis after the addition of the substrate surrogates pyruvamide and methyl acetylphosphonate.

We used a SAXS based assay for our experiments.

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